Overnight Collagen Reset Cream
An intensive overnight treatment powered by topical melatonin to deeply hydrate, repair the lipid barrier, and restore elasticity while you sleep.









Overnight Repair Benefits
Neutralizes free radical damage and oxidative stress accumulated during the day.
Plumps fine lines and restores elasticity with Hydrolyzed Collagen.
Thick, buttery micro-emulsion locks in 8-hour deep moisture without feeling greasy.
Clinically corrects stubborn pillow creases and thinning moisture barriers.
Stop Letting Biological Exhaustion Age Your Skin
During the day, your skin plays defense against UV, pollution, and oxidation. At night, it switches into crucial cellular repair mode. If you wake up with deep pillow creases and skin that feels tight or dry, your moisture barrier is failing to recover overnight.
The Overnight Collagen Reset Cream leverages this critical repair window. It infuses high-potency antioxidants and structural hydration directly into the lipid barrier, ensuring you wake up to a visibly rested, plumper complexion.
Proprietary Science
The Night-Cellular Melatonin Complex™
Formulated specifically for mature, thinning skin. While standard night creams rely solely on heavy, pore-clogging occlusives, our unique micro-emulsion delivers topical melatonin to neutralize oxidative stress.
- Topical Melatonin: A high-potency antioxidant that neutralizes free radical damage accumulated during the day.
- Hydrolyzed Collagen & Hyaluronic Acid: Plumps fine lines, restores skin elasticity, and provides 8-hour moisture barrier repair.
- Botanical Lipids: Deeply conditions dry, thinning, or hormonal skin while you sleep.
The Application
The Sensorial Nighttime Ritual
Prestige skincare requires intention. 45 minutes before sleep, take a quarter-sized amount of the rich, opaque cream.
Warm it gently between your fingertips for 5 seconds to match your exact body temperature. This crucial somatic step seamlessly activates the micro-emulsion.
Gently press—do not vigorously rub—the formula into the face, neck, and chest, allowing the active ingredients to lock in deep, restorative moisture overnight.
Clinical Repair
SCIENCE + PROOF
Visible Nighttime Results
The measure of a clinical night cream is its ability to plump, repair the lipid barrier, and reveal a visibly rested complexion by morning.
Clinical studies of our core active complex show massive improvements in barrier integrity, a reduction in the appearance of fine lines, and increased overnight moisture retention.
Increase in
Firmness
Wrinkles &
Fine Lines
Moisture
Retention
The Science & The Core Actives
Night-Cellular Melatonin Complex™: High-potency overnight antioxidant fusion that neutralizes daily oxidative stress and supports cellular night repair.
Hydrolyzed Collagen & Hyaluronic Acid: Plumps fine lines, rebuilds skin elasticity, and locks in 8-hour deep moisture.
Botanical Lipids & Avocado Oil: Deeply conditions dry, thinning, or hormonal skin while you sleep, reinforcing the lipid barrier without clogging pores.
How does this fit into my routine?
The Overnight Collagen Reset Cream is your Step 2 (PM). Apply 45 minutes before sleep to a clean face, or directly over your evening serums, to lock in repair actives.
Will this cream ruin my silk pillowcases?
No. The Overnight Collagen Reset Cream is formulated to penetrate deep into the lipid barrier within 5 minutes. It leaves your skin deeply hydrated and plump, not greasy, so your silk pillowcases remain pristine.
Is there anyone who shouldn't use this?
This cream contains melatonin — about 2.4 mg per ¼ tsp application. If you're pregnant or nursing, under 18, or managing a medical condition, check with your doctor before using it.
For external use only. Discontinue if irritation develops. If it gets in your eye, flush thoroughly with water.
What if it arrives too often, or not often enough?
Change the frequency, skip a delivery, or cancel from your account at any time. No email required, and no minimum number of orders.
Can I use this with Retinol?
Yes! Carmelwell's barrier-repairing formula pairs safely with retinoids. Apply your retinol product first, allow 5 minutes to absorb, and layer the Overnight Collagen Reset Cream on top to buffer dryness and soothe redness.
Overnight Collagen Cream — 2 oz
$64.80